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1

Relative biological effectiveness (RBE) values for proton beam therapy

Harald Paganetti, Andrzej Niemierko, Marek Ancukiewicz, Leo E Gerweck, Michael Goitein, Jay S Loeffler, Herman D Suit

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

2

Influence of nicotinamide on metabolic status, oxygen consumption, and radiation sensitivity at the cellular level

Gary M. Proulx, Syed T.H. Zaidi, Leo E. Gerweck

Journal:

Radiation Oncology Investigations

Year:

1996

Language:

english

File:

PDF, 428 KB

english, 1996

3

The pH difference between tumor and normal tissue offers a tumor specific target for the treatment of cancer

Journal:

Drug Resistance Updates

Year:

2000

Language:

english

File:

PDF, 69 KB

english, 2000

4

Radiation Sensitivity of Cultured Human Glioblastoma Cells 1

Gerweck, Leo E., Kornblith, Paul L., Burlett, Peg, Wang, Janice, Sweigert, Susan

Journal:

Year:

1977

Language:

english

File:

PDF, 349 KB

english, 1977

5

Tumor pH: Implications for treatment and novel drug design

Journal:

Seminars in Radiation Oncology

Year:

1998

Language:

english

File:

PDF, 656 KB

english, 1998

6

Relative biological effectiveness of proton beams in clinical therapy

Leo E. Gerweck, Sergey V. Kozin

Journal:

Radiotherapy and Oncology

Year:

1999

Language:

english

File:

PDF, 233 KB

english, 1999

7

Modification of Cell Lethality at Elevated Temperatures The pH Effect

Journal:

Radiation Research

Year:

1977

Language:

english

File:

PDF, 953 KB

english, 1977

8

Regulation of pH in Murine Tumor and Muscle

Leo E. Gerweck, Juong G. Rhee, Jason A. Koutcher, Chang W. Song and Muneyasu Urano

Journal:

Radiation Research

Year:

1991

Language:

english

File:

PDF, 710 KB

english, 1991

9

Lonidamine-Induced, pH Dependent Inhibition of Cellular Oxygen Utilization

John A. Stryker and Leo E. Gerweck

Journal:

Radiation Research

Year:

1988

Language:

english

File:

PDF, 613 KB

english, 1988

10

Topogram-based tube current modulation of head computed tomography for optimizing image quality while protecting the eye lens with shielding

Lin, Ming-Fang, Chen, Chia-Yuen, Lee, Yuan-Hao, Li, Chia-Wei, Gerweck, Leo E, Wang, Hao, Chan, Wing P

Journal:

Acta Radiologica

Year:

2018

Language:

english

File:

PDF, 409 KB

english, 2018

11

31P NMR spectra of extremity sarcomas: Diversity of metabolic profiles and changes in response to chemotherapy

Jason A. Koutcher, Douglas Ballon, Martin Graham, John H. Healey, Ephraim S. Casper, Robert Heelan, Leo E. Gerweck

Journal:

Magnetic Resonance in Medicine

Year:

1990

Language:

english

File:

PDF, 760 KB

english, 1990

12

The lack of correlation between heat and radiation sensitivity in mammalian cells

Leo E. Gerweck, Burlett Peggy

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1978

Language:

english

File:

PDF, 301 KB

english, 1978

13

Modification of pH induced cellular inactivation by irradiation—glial cells

Erwin M. Röttinger, Marc Mendonca, Leo E. Gerweck

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1980

Language:

english

File:

PDF, 429 KB

english, 1980

14

“Ultra” low dose-rate irradiation: Effects of prolonged exposures on population growth, survival and radiation sensitivity in cultured mammalian cells

William U. Shipley, Maureen Jennings, Leo E. Gerweck, C.Clifton Ling

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1980

Language:

english

File:

PDF, 175 KB

english, 1980

15

The influence of oxygen concentration on the response of cells exposed to single or fractionated heat treatments

Leo E. Gerweck, Franz Bascomb

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1981

Language:

english

File:

PDF, 107 KB

english, 1981

16

Influence of low pH on the development and decay of 42°C thermotolerance in cho cells

Leo E. Gerweck, Barbara Richards, Howard B. Michaels

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1982

Language:

english

File:

PDF, 1.01 MB

english, 1982

17

Tumor size dependent changes in a murine fibrosarcoma: Use of in vivo31P NMR for non-invasive evaluation of tumor metabolic status

Paul G Okunieff, Jason A Koutcher, Leo Gerweck, Eric Mcfarland, Bernard Hitzig, Muneyasu Urano, Thomas Brady, Leo Neuringer, Herman D Suit

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1986

Language:

english

File:

PDF, 863 KB

english, 1986

18

Radiation response of xenografts of a human squamous cell carcinoma and a glioblastoma multiforme: A progress report

Herman D. Suit, Anthony Zietman, Kathleen Tomkinson, Jonathan Ramsay, Leo Gerweck, Robert Sedlacek

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1990

Language:

english

File:

PDF, 1.09 MB

english, 1990

19

Relationship of changes in pH and energy status to hypoxic cell fraction and hyperthermia sensitivity

Jason A. Koutcher, Deborah Barnett, Alice B. Kornblith, David Cowburn, Thomas J. Brady, Leo E. Gerweck

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1990

Language:

english

File:

PDF, 832 KB

english, 1990

20

Energy status in the murine FSaII and MCaIV tumors under aerobic and hypoxic conditions: An in-vivo and in-vitro analysis

Leo E. Gerweck, Jason A. Koutcher, T.H. Syed Zaidi, Tara Seneviratne

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1992

Language:

english

File:

PDF, 671 KB

english, 1992

21

Simultaneous evaluation of determinants of radiocurability: Intrinsic cell radiosensitivity,, clonogenic fraction, and hypoxic fraction

Leo Gerweck, Anthony Zietman, Tanweer Zaidi

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1993

Language:

english

File:

PDF, 207 KB

english, 1993

22

Improved physiological parameters in murine & human tumors by nicotinamide

Intae Lee, Leo E. Gerweck, Yves Boucher, Thomas J. Demhartner, Christopher Mendello, Rakesh K. Jain

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1993

Language:

english

File:

PDF, 100 KB

english, 1993

23

Multivariate determinants of radiocurability I: Prediction of single fraction tumor control doses

Leo E. Gerweck, Syed T. Zaidi, Anthony Zietman

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1994

Language:

english

File:

PDF, 1.23 MB

english, 1994

24

Influence of nicotinamide on metabolic status, oxygen consumption, and radiation sensitivity at the cellular level

Gary M. Proulx, Leo E. Gerweck

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1994

Language:

english

File:

PDF, 150 KB

english, 1994

25

1052 Single and 30 fraction tumor control doses correlate in xenografted tumor models: Implications for predictive assays

Leo E. Gerweck, Willum Dubois, Michael Baumann, Herman D. Suit

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1995

Language:

english

File:

PDF, 112 KB

english, 1995

26

Enhancement of fractionated-dose irradiation by retinoic acid plus interferon

Leo E Gerweck, Syed T Zaidi, Thomas F Delaney

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1998

Language:

english

File:

PDF, 70 KB

english, 1998

27

Tumor growth retardation and pathophysiological effects of adenosine 5′-triphosphate therapy measured by thallium washout, 31P nuclear magnetic resonance, laser doppler flowmetry, and intradermal angiogenesis

Paul Okunieff, John Froio, Rajesh Soni, Julia Kahn, Leo Gerweck, Robert Zlotecki, Edward H. Abraham

Journal:

Radiation Oncology Investigations

Year:

1993

Language:

english

File:

PDF, 1.05 MB

english, 1993

28

Quantitative analysis of angiogenesis and growth of bone: effect of indomethacin exposure in a combined in vitro-in vivo approach

Michael Leunig, Fan Yuan, Leo E. Gerweck, David A. Berk, Rakesh K. Jain

Journal:

Research in Experimental Medicine

Year:

1995

Language:

english

File:

PDF, 2.27 MB

english, 1995

29

Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning

Pat Zanzonico, Joseph O’Donoghue, JDonald Chapman, Richard Schneider, Shangde Cai, Steven Larson, Bixiu Wen, Yuchun Chen, Ronald Finn, Shutian Ruan, Leo Gerweck, John Humm, Clifton Ling

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2004

Language:

english

File:

PDF, 567 KB

english, 2004

30

Intrinsic radiation sensitivity and split-dose recovery of glioblastoma multiforme

Alphonse Taghian, Herman Suit, Frank Pardo, Danielle Gioioso, Kathy Tomkinson, Willem duBois, Leo Gerweck

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1991

Language:

english

File:

PDF, 270 KB

english, 1991

31

In vitro intrinsic radiation sensitivity of glioblastoma multiforme

Alphonse Taghian, Herman Suit, Francisco Pardo, Danielle Gioioso, Kathleen Tomkinson, Willem DuBois, Leo Gerweck

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1992

Language:

english

File:

PDF, 1011 KB

english, 1992

32

The reproducibility and relationship between single and fractionated dose estimates of the surviving fraction at 2 Gy

Leo E. Gerweck, S. Tanweer Zaidi

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1996

Language:

english

File:

PDF, 792 KB

english, 1996

33

Perivascular nitric oxide gradients normalize tumor vasculature

Jain, Rakesh K, Fukumura, Dai, Kashiwagi, Satoshi, Tsukada, Kosuke, Xu, Lei, Miyazaki, Junichi, Kozin, Sergey V, Tyrrell, James A, Sessa, William C, Gerweck, Leo E

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

34

Killing of Chinese hamster cells in vitro by heating under hypoxic or aerobic conditions

Leo E. Gerweck, Edward L. Gillette, William C. Dewey

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 156 KB

english, 1965

35

Proton vs carbon ion beams in the definitive radiation treatment of cancer patients

Herman Suit, Thomas DeLaney, Saveli Goldberg, Harald Paganetti, Ben Clasie, Leo Gerweck, Andrzej Niemierko, Eric Hall, Jacob Flanz, Josh Hallman, Alexei Trofimov

Journal:

Radiotherapy and Oncology

Year:

2010

Language:

english

File:

PDF, 1.67 MB

english, 2010

36

Dose-rate effects in external beam radiotherapy redux

C. Clifton Ling, Leo E. Gerweck, Marco Zaider, Ellen Yorke

Journal:

Radiotherapy and Oncology

Year:

2010

Language:

english

File:

PDF, 235 KB

english, 2010

37

Factors Influencing the Oxidation of Cysteamine and Other Thiols: Implications for Hyperthermic Sensitization and Radiation Protection

John E. Biaglow, Rolf W. Issels, Leo E. Gerweck, Marie E. Varnes, Birgit Jacobson, James B. Mitchell and Angelo Russo

Journal:

Radiation Research

Year:

1984

Language:

english

File:

PDF, 459 KB

english, 1984

38

Lifetime Increased Cancer Risk in Mice Following Exposure to Clinical Proton Beam–Generated Neutrons

Gerweck, Leo E., Huang, Peigen, Lu, Hsiao-Ming, Paganetti, Harald, Zhou, Yenong

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2014

Language:

english

File:

PDF, 575 KB

english, 2014

39

Repair of Sublethal Damage in Mammalian Cells Irradiated at Ultrahigh Dose Rates

Leo E. Gerweck, Edward R. Epp, Howard B. Michaels, C. Clifton Ling and Eleanor C. Peterson

Journal:

Radiation Research

Year:

1979

Language:

english

File:

PDF, 1.45 MB

english, 1979

40

Enhancement of Mammalian Cell Sensitivity to Hyperthermia by pH Alteration

Leo Gerweck and Erwin Rottinger

Journal:

Radiation Research

Year:

1976

Language:

english

File:

PDF, 384 KB

english, 1976

41

Response of a Spontaneous Murine Tumor to Hyperthermia: Factors Which Modify the Thermal Response in Vivo

Muneyasu Urano, Leo E. Gerweck, Roger Epstein, Mary Cunningham and Herman D. Suit

Journal:

Radiation Research

Year:

1980

Language:

english

File:

PDF, 877 KB

english, 1980

42

The Influence of Variable Oxygen Concentration on the Response of Cells to Heat or X Irradiation

Leo E. Gerweck, Barbara Richards and Maureen Jennings

Journal:

Radiation Research

Year:

1981

Language:

english

File:

PDF, 217 KB

english, 1981

43

Persistence of Thermotolerance in Slowly Proliferating Plateau-Phase Cells

Leo E. Gerweck and Thomas F. DeLaney

Journal:

Radiation Research

Year:

1984

Language:

english

File:

PDF, 283 KB

english, 1984

44

Cell Proliferation, Protein Turnover, and the Decay of Thermotolerance in CHO Cells

Leo E. Gerweck and L. F. Epstein

Journal:

Radiation Research

Year:

1986

Language:

english

File:

PDF, 1.21 MB

english, 1986

45

Variability in the Kinetics of Thermotolerance Decay in Three Cell Lines

Leo E. Gerweck and Hideyuki Majima

Journal:

Radiation Research

Year:

1987

Language:

english

File:

PDF, 729 KB

english, 1987

46

Relationship between Energy Status, Hypoxic Cell Fraction, and Hyperthermic Sensitivity in a Murine Fibrosarcoma

Leo E. Gerweck, Muneyasu Urano, Jason Koutcher, Mary Pat Fellenz and Julia Kahn

Journal:

Radiation Research

Year:

1989

Language:

english

File:

PDF, 1.07 MB

english, 1989

47

Influence of Extracellular pH on Intracellular pH and Cell Energy Status: Relationship to Hyperthermic Sensitivity

Mary Pat Fellenz and Leo E. Gerweck

Journal:

Radiation Research

Year:

1988

Language:

english

File:

PDF, 903 KB

english, 1988

48

Influence of Nutrient and Energy Deprivation on Cellular Response to Single and Fractionated Heat Treatments

Leo E. Gerweck, W. K. Dahlberg, L. F. Epstein and D. S. Shimm

Journal:

Radiation Research

Year:

1984

Language:

english

File:

PDF, 298 KB

english, 1984

49

Oxygen Sensitization of Mammalian Cells under Different Irradiation Conditions

C. Clifton Ling, Howard B. Michaels, Leo E. Gerweck, Edward R. Epp and Eleanor C. Peterson

Journal:

Radiation Research

Year:

1981

Language:

english

File:

PDF, 451 KB

english, 1981

50

Prolonged "Ultra" Low-Dose-Rate Irradiation: Effects on Chinese Hamster Cell Population Growth, Survival, and Radiation Sensitivity

William U. Shipley, Maureen Jennings, Leo E. Gerweck and C. Clifton Ling

Journal:

Radiation Research

Year:

1981

Language:

english

File:

PDF, 312 KB

english, 1981